El Hospital Istiklal es el único centro en Jordania que integra servicios de salud mental con todas las especialidades médicas para reducir el estigma de los pacientes. El dedicado Centro Mutmainna ofrece asesoramiento psicológico, terapia conductual y apoyo médico especializado. Como centro de capacitación en trauma para el Colegio Estadounidense de Cirujanos, la clínica cuenta con acreditación de la HCAC. La Oficina de Servicios Internacionales para Pacientes ayuda con visas médicas y traslados al aeropuerto. La atención se lleva a cabo dentro de un entorno hospitalario general de gran escala, ofreciendo acceso a Suites Reales y apoyo para programas de residencia e investigación psiquiátrica.
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La atención cardiovascular es un foco principal, con más de 5000 cirugías a corazón abierto realizadas. El departamento de urgencias ha atendido más de 1 500 000 casos. El hospital cuenta con la acreditación HCAC, renovada en ocho ocasiones con una puntuación del 98,4 %. Es también un centro de formación en traumatología del Colegio Americano de Cirujanos. Entre sus unidades especializadas se incluyen un centro de fertilidad y un programa de trasplante de médula ósea.
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