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end-stage osteoarthritis with major deformity","Immunosuppression or uncontrolled systemic disease","Allergy to anesthetic or product components"],"days_in_clinic":{"min":0,"max":1,"unit":"nights","qualifier":"Usually same-day procedure; overnight stay only if protocol or patient condition requires."},"diagnostic_duration_minutes":null,"diagnostic_preparation":null,"diagnostic_referral_needed":null,"diagnostic_result_time_hours":null,"exercise_resume_weeks":{"min":2,"max":6,"unit":"weeks","qualifier":"Low-impact exercise sooner; high-impact activity after clinician clearance."},"final_result_months":{"min":3,"max":6,"unit":"months","qualifier":"Symptom change often assessed around 3-6 months; response varies widely."},"fly_home_after_days":{"min":1,"max":3,"unit":"days","qualifier":"Depends on harvest site comfort, knee swelling and physician clearance."},"follow_up_visits":[{"purpose":"wound_check","after":{"min":1,"max":3,"unit":"days","qualifier":"Check of harvest and injection sites before flying home."},"requirement":"routine"},{"purpose":"result_review","after":{"min":90,"max":180,"unit":"days","qualifier":"Symptom review, often done remotely for international patients."},"requirement":"conditional"}],"indications":["Symptomatic knee osteoarthritis, mild to moderate","Persistent knee pain despite conservative treatment"],"main_risks":["Infection and allergic or immune reactions possible.","Harvest-site bleeding, bruising or hematoma","Product contamination or variable cell quality"],"pain":"Mild to moderate soreness at the harvest site and knee for several days, with temporary swelling. Usually managed with simple analgesics and rest.","preparation":["Blood tests and infection screening before harvest","Review of anticoagulants and blood-thinning medications","Stop anti-inflammatory drugs about one week before","Pre-procedure physician consultation and knee examination"],"recovery_timeline":[{"phase":"Harvest day","description":"Soreness, bruising and dressing at harvest site; knee may feel stiff.","restrictions":["Keep harvest site clean and dry","No heavy lifting with harvest-side arm or leg"]},{"phase":"Days 2-14","description":"Harvest soreness and knee swelling gradually settle; walking usually resumes.","restrictions":["Avoid running, jumping and strenuous knee exercise","No swimming until harvest site has healed"]},{"phase":"Weeks 2-6","description":"Gradual return to low-impact activity as knee comfort allows.","restrictions":["Avoid high-impact sports until cleared"]}],"rehabilitation_days":{"min":7,"max":14,"unit":"days","qualifier":"Light home exercises and optional physiotherapy; pace depends on knee swelling and harvest-site comfort."},"result_longevity":"Pain relief typically lasts 12-24 months, then gradually fades; a repeat injection may be considered.","revision_rate_pct":{"min":10,"max":30,"unit":"percent","qualifier":"Repeat injection or conversion to other treatment within 2 years due to insufficient benefit."},"scars":"No visible scar from injection; a tiny puncture mark may remain at the harvest site.","sessions_or_stages":{"sessions":{"min":1,"max":2,"unit":"visits","qualifier":"Usually a single harvest and injection session; some protocols add a repeat injection."},"stages":[{"code":"cell_harvest","label":"Cell harvest from bone marrow or fat","after":{"min":0,"max":0,"unit":"days","qualifier":"Same day as injection."}},{"code":"knee_injection","label":"Processed cells injected into knee joint","after":{"min":0,"max":0,"unit":"days","qualifier":"Same session after processing."}}],"qualifier":"Single-session harvest and injection is typical; repeat injection depends on protocol."},"success":{"metric":"Patients with meaningful knee pain relief","value":65,"unit":"percent","horizon":"6-12 months","population":"Adults with mild to moderate knee osteoarthritis; bone marrow aspirate concentrate or adipose-derived cells","evidence_status":"limited"},"techniques":[{"name":"Bone marrow aspirate concentrate injection","suits_whom":"Adults with knee osteoarthritis; marrow harvested from iliac crest under local anesthetic","recovery":"Same-day discharge; harvest-site puncture soreness for several days."},{"name":"Adipose-derived stromal cell injection","suits_whom":"Adults with knee osteoarthritis; fat harvested from abdomen under local anesthetic","recovery":"Same-day discharge; harvest-site bruising and soreness for several days."}],"treatment_conditions":["outpatient"],"treatment_duration_hours":{"min":1.5,"max":3,"unit":"hours","qualifier":"Includes harvest, cell processing and injection; varies with cell source and processing method."},"initial_assessment_documents":["Knee MRI report","Knee X-ray report","Orthopedic diagnosis or clinic notes","List of blood thinners","Previous knee injections or surgery records"],"travel_trips":{"min":1,"max":2,"one_trip_possible":true,"qualifier":"Usually a single-session cell harvest and injection with a 1-3 day stay; some protocols add a repeat injection."}}},"hrefLanguages":[{"rel":"alternate","hreflang":"ru","language":"ru","href":"https://ru.bookimed.com/clinics/country=poland/city=rzeszow/procedure=vosstanovlenie-kolennogo-sustava-stvolovymi-kletkami/"}],"questionsAndAnswers":[],"seoTests":{"thin_content":false,"no_txt_after_3_clinics":false},"offerFilters":{"offer_count":0,"price_filter":{"from":0,"to":0,"avg":0}},"leadsCount":{"leads_count":2},"manualSeo":[],"updatedAt":"2026-11-05T03:30:11.000Z","activeCountries":["PL","ES","TR","TH"],"hasVideoReviewsByContext":true,"hasCriticalApiFallback":false}