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Prof. Amos Toren

MD, PhD, MHA | Pediatric Hemato-Oncology & Bone Marrow Transplant Specialist

Department:

Pediatric Hemato-Oncology & BMT Division, Sheba Medical Center

Languages:

Hebrew, English

Professional Summary

Inside Sheba’s Hematology Ecosystem: Expertise Recognized by Forbes Israel

Prof. Amos Toren is a highly experienced pediatric hemato-oncologist and former Director of the Pediatric Hemato-Oncology and Bone Marrow Transplant Division at Sheba Medical Center. He is board-certified in pediatrics, general hematology, and pediatric hemato-oncology, with additional academic qualifications in genetics and healthcare management.

Prof. Toren is internationally recognized for his work in advanced therapies for pediatric cancers, particularly in the fields of immunotherapy and bone marrow transplantation. His clinical approach combines cutting-edge research with individualized treatment strategies for complex and high-risk cases.

Areas of Expertise

Pediatric oncology and hematologic malignancies

Leukemia and lymphoma in children and young adults

Bone marrow and stem cell transplantation

Immune deficiencies and chronic blood disorders

Treatment of rare and complex pediatric cancers

Advanced cellular therapies (including CAR T-cell approaches)

Education & Academic Background

MD, Faculty of Medicine, Tel Aviv University, Israel

Residency in Pediatrics, Sheba Medical Center

Residency in Hematology, Sheba Medical Center

Specialization in Pediatric Hemato-Oncology and Bone Marrow Transplantation, Hadassah Medical Center

PhD in Human Genetics, Tel Aviv University

Master of Health Administration (MHA), Recanati Business School, Tel Aviv University

Clinical & Research Experience

Prof. Toren has led one of Israel’s most advanced pediatric oncology and transplantation programs, treating both children and young adults (up to age 30) with complex malignancies.

His research focuses on:

CAR T-cell therapy for relapsed and resistant leukemias and lymphomas

cellular immunotherapy approaches (including cytokine-induced killer cells)

pediatric brain tumors

innovative targeted treatments in pediatric oncology

He is actively involved in translational research aimed at improving outcomes in treatment-resistant cancers.

International Collaboration

The department led by Prof. Toren maintains strong collaborations with leading global institutions, including:

St. Anna Children’s Hospital (Austria)

National Cancer Institute (NIH), USA

St. Jude Children’s Research Hospital, USA

Academic & Professional Roles

Former Director, Pediatric Hemato-Oncology & BMT Division

Former Head of Hematology Division, Tel Aviv University (two terms)

Member of leading international societies:

American Society of Hematology (ASH)

Children’s Oncology Group (COG)

European Society of Pediatric Hematology (ESPHI)

European Group for Blood and Marrow Transplantation (EBMT)

Center for International Blood and Marrow Transplant Research (CIBMTR)

Member, Israeli Ministry of Health Cord Blood Committee

Board Certifications

Pediatrics

Pediatric Hemato-Oncology

Bone Marrow Transplantation

Selected Publications

Immunoglobulin prophylaxis in pediatric stem cell transplantation

Overcoming resistance to PARP inhibitors in cancer therapy

Additional peer-reviewed publications in pediatric oncology and hematology

Why Patients Choose Prof. Toren

Extensive experience in complex pediatric oncology and transplantation

Expertise in advanced immunotherapies (including CAR T-cell approaches)

Strong integration of research and clinical practice

Leadership in a Top-10 globally ranked hospital

Experience with rare and treatment-resistant cases

El Dr. Abraham Avigdor, MD, es director del Instituto de Hematología y codirector de la División de Hematología y Trasplante de Médula Ósea del Centro Médico Sheba. Es un líder internacional en linfomas, CAR‑T y hemato‑oncología avanzada, con más de 35 años de experiencia. Su enfoque clínico incluye linfomas, mieloma múltiple y cánceres hematológicos complejos.

Es pionero en la integración de CAR‑T. Dirige programas de terapia celular y trasplante de médula ósea (autólogo y alogénico). Además, impulsa terapias con células madre y diagnósticos de precisión, incluidos pronósticos basados en PET/TC. Su labor abarca inmunoterapia y regímenes dirigidos, así como el desarrollo de protocolos innovadores basados en datos.

Colabora con LYSA, EMCL y grupos internacionales de PET. Es autor de más de 130 publicaciones. Cargos clave: fundador y presidente del Israeli Lymphoma Working Group, ex presidente del Israeli Lymphoma Study Group y profesor sénior en la Universidad de Tel Aviv. Formación: MD, Universidad Ben‑Gurión; residencia, Centro Médico Sheba; beca posdoctoral, Instituto Weizmann. Premios: Premio de la Knéset, Premio del Ministerio de Salud de Israel y Premio Sackler.

El Prof. Avichai Shimoni, MD, es director de Trasplante de Médula Ósea del Sheba Medical Center. Es hemato-oncólogo con más de 30 años de experiencia en trasplante de médula ósea, terapias celulares y atención avanzada del cáncer de la sangre.

Dirige un programa de alto volumen para cánceres de la sangre complejos y de alto riesgo. Realiza trasplantes alogénicos y autólogos. También ofrece terapia con células CAR T para leucemia, linfoma y mieloma múltiple. Realizó una subespecialización en trasplante de médula ósea en el MD Anderson Cancer Center.

Es jefe del Departamento de Hematología de la Universidad de Tel Aviv y profesor de Hematología. Ha publicado más de 250 artículos científicos. Su investigación se centra en la terapia con células CAR T y el trasplante de células madre. Suele figurar entre los mejores médicos de Israel (Forbes 2025 y 2026).

Dr. Hana Golan

MD | Pediatric Hematology-Oncology & Bone Marrow Transplant Specialist

Department:

Pediatric Hemato-Oncology & BMT Division, Sheba Medical Center

Languages:

Hebrew, English

Professional Summary

Dr. Hana Golan is a leading pediatric hemato-oncologist and Director of the Pediatric Hemato-Oncology and Bone Marrow Transplant (BMT) Division at Sheba Medical Center. She specializes in the treatment of childhood cancers and complex hematological disorders, with a particular focus on neuroblastoma and high-risk solid tumors.

With decades of clinical and research experience, Dr. Golan combines advanced oncology protocols with personalized treatment strategies aimed at improving outcomes in challenging pediatric cases.

Areas of Expertise

Pediatric oncology (solid tumors and hematologic malignancies)

Neuroblastoma (including high-risk cases)

Bone marrow and stem cell transplantation

Leukemia and lymphoma in children

Chronic and inherited blood disorders

Immune deficiencies and metabolic disorders

Personalized chemotherapy and targeted therapy protocols

Education & Training

MD, Rappaport Faculty of Medicine, Technion – Israel Institute of Technology

Residency in Pediatrics, Sheba Medical Center

Residency in Pediatric Hematology-Oncology, Sheba Medical Center

Advanced research training in transplantation immunology, Weizmann Institute of Science

Additional training in clinical research, biomedical informatics, and healthcare management

Clinical & Research Experience

Dr. Golan leads one of the most advanced pediatric oncology programs in the region, managing complex and high-risk cases. She is actively involved in the development and implementation of international treatment protocols, particularly in neuroblastoma.

Her research focuses on:

cancer stem cells in pediatric tumors

development of targeted therapies

novel approaches to treatment-resistant malignancies

emerging therapeutic strategies, including cannabinoid-related research in oncology

Clinical Trials & International Collaboration

Principal Investigator of the High-Risk Neuroblastoma ESIOP protocol

Investigator in international Phase I/II clinical trials targeting advanced pediatric cancers

National coordinator of multicenter oncology protocols

Academic & Teaching Roles

Senior Lecturer, Sackler Faculty of Medicine, Tel Aviv University

Lecturer in pediatric hematology-oncology for physicians and nurses

Coordinator of hematology training programs for medical students

Leadership & Innovation

Director, Pediatric Hemato-Oncology and BMT Division

Led implementation of computerized chemotherapy protocols and patient databases

Developed systems to improve clinical workflow and patient safety

Board Certifications

Pediatrics

Pediatric Hematology-Oncology

Selected Publications

Primary immunodeficiency syndromes in Israel

Integration of palliative care in pediatric oncology

Additional peer-reviewed publications in pediatric cancer treatment

Why Patients Choose Dr. Golan

Extensive experience in complex pediatric oncology cases

Leadership in international clinical trials and treatment protocols

Expertise in neuroblastoma and high-risk pediatric tumors

Multidisciplinary approach combining treatment, research, and supportive care

Practice within a Top-10 globally ranked hospital