Tratamiento en Milán (Italia)

El profesor Stefano Boriani es un cirujano ortopédico de renombre mundial y autor de un sistema de estadificación quirúrgica único de tumores espinales y técnicas de resección de tumores. Ha realizado más de 3000 procedimientos quirúrgicos, escrito más de 430 artículos de investigación e inventado un sistema de fibra de carbono para la reconstrucción de tumores. También es profesor en la Escuela de Postgrado de Ortopedia de la Universidad de Bolonia y miembro honorario de varias sociedades de columna. También es el fundador de una asociación sin fines de lucro en Mozambique que apoya actividades médicas y capacita a cirujanos locales.

Ortopedista, Oncólogo, Especialista en tratamiento de osteosarcoma

Neurocirujano de columna

Cirujano ortopédico

Cirujano de columna

El Dr. Roberto Bassani ha realizado más de 2500 operaciones quirúrgicas importantes de columna en la columna cervical, torácica y lumbar.

Prof. Alessandro Repici is the Director of the Gastroenterology and Digestive endoscopy Unit in Humanitas Research Hospital. Graduated in Medicine and Surgery in 1990 and the following year he won a scholarship at the Department of Gastroenterology Molinette hospital in Turin, where he began his practice in digestive endoscopy. In 1992, he worked with Prof. Claude Liguory as a fellow at the American Hospital in Paris.

In 1994 he became a specialist in Gastroenterology and Digestive Endoscopy at the University of Messina and worked in the Department of Gastroenterology, Ospedale Maggiore Molinette of Turin.

In the following years, he has been working at the Service of Digestive Endoscopy of Altona Hospital in Hamburg, directed by prof. Hagenmuller, and in the Department of Gastroenterology Molinette Hospital in Turin, directed by prof. Rizzetto. In 1999, he was a Research Fellow at the Center for Oncological and Operative Endoscopy of Wellsley Hospital in Toronto.

He teaches Gastroenterology and Digestive Endoscopy at the School of Specialization in Oncology since 2000, at the University of Turin since 2004 and Endoscopy Diagnostic Techniques and Operations at the School of Specialization in General Surgery I and II of the University of Turin.

The clinical activity and research of Prof. Repici mainly focuses on the development of new endoscopic techniques in the field of diagnosis and therapy, with particular attention to new methods of endoscopic removal of cancerous lesions and early in the palliation of advanced gastrointestinal malignancies.

Prof. Repici is coordinator, principal investigator and co-investigator in more than 50 studies, including phase II and III for FDA and EMA approval of new molecules and new instruments for diagnostic and operational endoscopy. 

Prof. Repici collaborates on research projects in the field of endoscopy with the University of Rotterdam, in Haifa, in New York and with several Italian centers. He is a member of various national and international scientific society of Gastroenterology and Digestive Endoscopy.

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=repici+alessandro

Prof. Andrea Lania has graduated at the Università degli Studi of Milan and is specialized in endocrinology. He is the Unit Director of Endocrinology and Diabetology in Humanitas Research Hospital and his specialization is pituitary diseases, pituitary adenomas, thyroid cancer, pancreatic neuroendocrine tumors, poorly differentiated neuroendocrine carcinomas.

Medical areas of interest:
Pituitary tumors, hypopituitarism, acromegaly, Cushing’s disease and syndrome, neuroendocrine tumors, thyroid and thyroid diseases, adrenal and adrenal diseases, hypogonadism.

Research areas of interest:
Study of the pathogenetic mechanisms of pituitary and neuroendocrine tumors, of the molecular mechanisms responsible for the different response of pituitary and neuroendocrine tumors to medical therapy.

Prof. Lania published 198 peer-reviewed papers (Google Scholar H-Index 47; Scopus H-Index 38, cit tot 4604)

Prof. Lania has a long standing expertise in the field of intra-cellular signaling in endocrine tumors. In particular, in the past ten years, he contributed to analyze the role of PKA regulatory subunits in the pathogenesis and control of cell proliferation of endocrine tumors. Moreover, he contributed to define the role of SSTR5 domains involved in the intracellular trafficking of this receptor in human pituitary cells and to analyze the impact of DR2R and SSTR2&5 polymorphic variants on both the clinical outcome and response to medical treatment in patients with pituitary tumors.

Recently, he contributed to identify the role of cytoskeleton protein FLNA in mediating both intracellular signaling and membrane targeting of somatostatin type 2 receptor and D2R in pituitary and pancreatic neuroendocrine tumors. Finally, he contributed to explore the intracellular mechanisms possibly involved in mediating the interplay between drugs commonly used in the treatment of neuroendocrine tumors.

Previous experience:
2005-2008 Fondazione Ospedale Maggiore Policlinico IRCCS, Milan, Italy
Director of Endocrinologic Day Hospital and surgery on pituitary disorders. 

Publications: https://www.ncbi.nlm.nih.gov/pubmed?term=lania%20A 

Dr. Corrado Lodigiani has been assistant at the Thrombosis Centre of Humanitas research Hospital from 1998 to 2013 and he became Unit Director in 2013. 

Humanitas Thrombosis Center is a state-of-the-art service for the proper management of the diagnosis and therapy of venous thromboembolic pathology (deep and superficial venous thrombosis, pulmonary thromboembolism, visceral venous thrombosis) and arterial (myocardial infarction, cerebral stroke, peripheral arterial disease). 
Other also rare diseases treated are atypical thrombosis, such as the vascular circulation of the retina, the hearing system and the placental circulation during pregnancy. 

Dr. Lodigiani adopts the multidisciplinary approach and works in collaboration with all medical and surgical specialties. In particular, he carries out clinical and instrumental diagnostics (vascular ecocolordoppler) and research on the causes, diagnosis and therapy of thrombotic and bleeding disorders, congenital and acquired. His clinical activity also involves the diagnosis and management of patients suffering from bleeding diseases, such as haemophilia, von Willebrand’s disease and platelet diseases.

Medical areas of interest:  

In recent years, he has devoted himself with particular interest to the testing, in the role of Principal Investigator in International Clinical Studies, of new antithrombotic drugs and, above all, anticoagulants, which are about to be marketed and will constitute a valid and safe alternative to traditional oral anticoagulant therapy (DOACs). He is also working, with great interest, on researching the causes of idiopathic infertility and the usefulness and effectiveness of some therapeutic strategies, such as the use of anticoagulant drugs, improving the results of artificial insemination procedures. He is the author of numerous articles in international scientific journals and speaker at numerous national and international conferences.

Dr. Giuseppe Marinari is a specialist in general surgery (1991) and nutrition (1995). He started his career in Bariatric Surgery in 1987 and, since then, he has performed over 7000 bariatric procedures, mainly Sleeve Gastrectomy, Gastric Bypass, and Biliopancreatic Diversion. Dr. Giuseppe Marinari has international experience, and he is one of the leading Bariatric surgeons in Italy. Over the past 10 years, he has focused on the implementation of a high-volume centre (>1250 procedures in 2019). Since 2016, he adopted an Enhanced Recovery After Bariatric Surgery (ERABS) protocol, to improve benefits for the patient. In essence, this means a faster recovery and an early return to daily activities, with a very high patient approval rating.

Obesity is a complex condition that encompasses a variety of comorbidities. Therefore, the role of a bariatric surgeon is multidisciplinary, including the understanding (and sometimes treating) of comorbidities as well as performing surgery.

Bariatrics interested Dr. Giuseppe Marinari at first because it was a new and growing field. He then developed an appreciation for the multidisciplinary aspect. Now Dr. Giuseppe Marinari is eager to help people transform their lives.

Dr. Giuseppe Marinari  was mentored by Prof. N. Scopinaro at the University Hospital in Genoa, Italy. He invented the biliopancreatic diversion (with or without duodenal switch), a malabsorptive bariatric operation. Dr. Marinari is now Director of the Bariatric Center. He has international experience and is one of the leading surgeons in his field. He performs both restrictive and malabsorbative bariatric procedures, mainly using the laparoscopic approach. In Humanitas Reasearch Hospital patients are treated by a multi-disciplinary team. The patients are given full attention and support throughout all the steps along the treatment.

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=marinari+giuseppe

Dr. Federico Pessina is the Cranial Neurosurgey Unit Director.

Medical areas of interest: Brain tumors, glioblastomas, low grade gliomas, brain metastases, meningiomas, neuromas, cavernous angiomas, brain aneurysms

Surgical treatment with brain mapping techniques, awake and minimally invasive surgery of all central nervous system tumors.

Surgical treatment of highly complex tumors of the skull base and cranio-cervical hinge: meningiomas, neuromas, craniopharyngiomas, brain stem tumors.

All the tumor pathologies described above are addressed after multidisciplinary multi-specialist evaluation.

The surgical approach is customized to the patient and to the type of lesion, making use of the most advanced intraoperative techniques for malignant brain tumors (neuronavigation, intraoperative neurophysiology, intraoperative CT) and more complex approaches (anterior, posterior and combined petroosectomies, minimally invasive accesses) for benign diseases of the skull base such as meningiomas and neuromas.

Research areas of interest: Experimental protocols in the treatment of glioblastomas

- Prospective protocols in the treatment of brain metastases

- Role of surgical removal and integrated treatments in glioblastomas and malignant brain tumors

- Intracranial meningiomas

- Cadaver lab dissection

Author of more than 60 scientific publications and 5 book chapters, he is member of Italian Society of Neurosurgery (SINCH).

In 2018 he joined the Scientific Committee of European Society of Neuroncology (EANO) and the Skull Base Surgery Committee of World Federation of Neurosurgical Society (WFNS).

Specialized training: 

Prof. Pessina obtained his Degree in Medicine and Surgery in University of  Insubria,  Varese, where he also completed his Residency Program.

From 2007 to 2008 he covered the role of Clinical Fellow in Neurosurgery in Lausanne University Hospital, focusing on image-guided intrinsic brain tumors resection and vascular neurosurgery

In 2018 he covered the Skull Base fellow position in Lariboisiere Hospital, Paris, fully dedicating to skull base surgery and hands-on dissection practice and teaching.

Since 2022, he is Full Professor in Neurosurgery (MED/27) in Humanitas University

Additional information of interest:

Member of the Scientific Committee of the European Association of Neuroncology (EANO)

Publications:  https://www.ncbi.nlm.nih.gov/pubmed/?term=Pessina+Federico

Dr. Daniela Pini is the Head of the Cardio-respiratory rehabilitation Unit.

Medical areas of interest: Dr. Daniela Pini has been working and researching heart failure and has gained considerable experience in the management of advanced forms of this pathology. She is also very interested in the evaluation and "overall" management of patients suffering from this disease, which mainly affects elderly people and who already have other chronic diseases, which, if neglected, can easily impair the effectiveness of treatment for heart failure itself.

Research areas of interest: new therapies for advanced heart failure: replacement therapy of the heart with mechanical assistance devices to the circulation or heart transplant. New drugs and devices. Multidisciplinary patient management programs.

Further information of interest: thanks to the high competence of cardiosurgeons, electrophysiologists and hemodynamists, Humanitas can count, as a clinical cardiologist, on a team that allows it to offer the patient all the range of therapeutic options for heart failure.

From June 2000 to October 2001 she was Visiting Assistant Professor at the Cardiovascular Division Hospital of the University of Pennsylvania. During this period, she worked in the Heart Failure/Heart Transplantation Program, where she participated in the management of patients with advanced heart failure waiting for transplantation, dealing in particular with medical complications in patients with mechanical assistance devices. She has also worked with kidney, kidney-pancreas, pancreas-insulae, lung, liver and heart transplant teams, dealing with the multiple aspects of managing solid organ transplant recipients.

She worked in the Niguarda Ca' Granda Hospital, at the Cardiomyopathy and Heart Transplantation Service, dealing mainly with patients with advanced heart failure and undergoing a cardiac transplant.

Dr. Pini is a member of the coordination committee of the Decompensation Area of the National Association of Medical Hospital Cardiologists – ANMCO. In the last two years she has been mainly concerned on building a network of “heart failure clinics” on the national territory.

Prof. Raffaello Furlan is the Unit Director of the Internal Medicine Center Unit.

Since 1990 he has been focusing his clinical interests on hypotensive phenomena and episodes of loss of consciousness, organizing and developing a functional multidisciplinary unit called "Syncope and Posture Disorders Unit", as part of the Internal Medicine Unit where he worked (currently Medical Clinic, Istituto Clinico Humanitas, Rozzano, and in the past L. Sacco Hospital, Milan, and Bolognini Hospital, Bergamo). 

This unit is composed of a neurologist, an endocrinologist, a cardiologist and a psychiatrist, in accordance with clinical-care facilitated protocols. Thanks to this organizational structure, and thanks to the use a special clinical laboratory, more than 1600 tilt tests have been carried out, together with intensive work with outpatients and inpatients, which led to the care of patients also from other regions in Italy and abroad (France, Switzerland, Australia, Comoros Islands and United States).

The Syncope and Posture Disorders Unit is currently part of a worldwide network of centres that refer to the National Dysautonomia Research Foundation, an American non-profit foundation providing advice and support to patients with different types of dysautonomia and financing international research protocols on the subject.  

Research areas of interest:

From 1977 to 1984, he took an active part in studies conducted on experimental models, to clarify the nervous mechanisms of cardiac, cardio-vascular and vascular reflexes involved in the regulation of blood pressure and in the genesis of cardiac pain. He also applied techniques of direct recording of sympathetic nerve activity and spectral analysis to the study of cardiovascular variability in the physiological, pathophysiologic and pathological  fields, studying the changes in the nervous control of the cardiovascular system during postural changes, physical training, neuromediated syncope in patients suffering from dysutopianism (Pure Autonomic Failure), and in subjects with Chronic Orthostatic Intolerance, Fibromyalgia, Esophageal Reflux Disease, Ulcerative Colitis and Parkinson’s disease. 

Since January 2004, the Syncope Unit directed by Prof. Furlan has conceived, realized and coordinated some observational multicentric studies aimed at studying the short-term prognosis of syncope, to evaluate the effectiveness of risk scales in the emergency room and the role of clinical judgement (steps studies, Short Term Prognosis of Syncope). The Syncope Unit was also an active part of EGSYS2 and other multicenter syncope studies. Currently, a study is underway to assess the effects of bilateral plantar stimulation on the path and neurovegetative profile of cardiovascular regulation in Parkinson’s disease. It involves 10 hospitals sponsored by the Lombardy region on syncope costs and a multicentric European study on the use of neuronal networks for syncope management in the emergency room.

Previous experience:

2007-2012 Hospital, Seriate, Italy
Director of Internal Medicine Unit, Outpatients and Day Hospital for medicine. 
1982-2007 Hospital, Milan, Italy
• Hospital assistant of Internal Medicine (Medicine II) until 1990. During this period, he was directly responsible for 8 beds in this Department and carried out regular call duties in the A&E Department. He was also involved in invasive measurements of blood pressure.

• Co-manager assistant in Internal Medicine (Medicine II; from February 1990). During this period, he was responsible for 12-18 beds of the Medicine Department, coordinating the work of two assistants. From January 2002 to January 2005 he had the title of "High Specialisation" in the field of disorders from orthostatic intolerance. From January 2005 he was responsible for the simple structure "Unit for Syncopes and Posture Disorders". 
• Following the incorporation process of Italian hospitals (as from 1996), he was involved in programmes for the ottimization of efficiency and cost reduction of the Medicine II Department and he had an active part in the discussion of the annual budget from 1998. He was responsible for the Day Hospital in Medicine II until January 2005. 

• He followed the course for Directors of Complex Operative Units, hospital area, edition UBMDSCO0201, held at the School of Management in Health of the Lombardy Region (I.Re.F.) in 2002, discussing the final project entitled "Evaluation of diagnostic performance and cost analysis of tilt test in the diagnosis of syncopal episodes", obtaining the resulting certification.

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=furlan r

Prof.  Roberto Gatti is the Physiotherapy Unit Director in Humanitas Research Hospital. Prof. Roberto Gatti became physiotherapist in 1985 at the University of Milan (Italy). In 1996 he got the licénce en kinésithérapie et réadaptation  at the Catholique University of Louvain la Neuve (Belgium) and, in 2009, the Master of sciences in Rehabilitation Sciences at the University of Florence (Italy).

Medical areas of interest: 

motor rehabilitation

Previous experience:
 

Didactic coordinator of Physiotherapy degree programme of the Vita-Salute San Raffaele University

• Group Leader of the Motor Function Analysis and Rehabilitation Laboratory of the Department of Neuroscience of San Raffaele Hospital
• Head of physiotherapy at San Raffaele Hospital

Research areas of interest:

Research lines of Prof. Roberto Gatti are mainly addressed on Biomechanics and Neurorehabilitation, with a focus on the effects of cognitive facilitations (i.e. action observation) on motor relearning of subjects with lesion at the central nervous system. As Biomechanics research lines his interest is focused on the study of anticipatory postural adjustments and their coordination with the agonist component of movement.

Teaching experience: 

Associated Director of the Physiotherapy degree programme of Humanitas Research Hospital since 2016

Prof. Efrem Civilini  is chairman at Humanitas University and Vascular Surgery Unit Director at Humanitas Research Hospital.

He received his medical degree from the University of Milan, Italy and board-certified in Vascular Surgery at the University of Siena, Italy. He took his internship and residency in vascular surgery at San Raffaele Scientific Institute, Milan (Italy) where he completed his training with clinical and research fellowships under the guidance of his mentor Prof. Roberto Chiesa.

As an attending surgeon and later as chief of Thoracic Aortic Surgery at the Cardiovascular Department of San Raffaele he practiced his surgical skills in an internationally recognized team treating thoraco-abdominal aneurysms and then studied minimally invasive aortic surgery at the Cleveland Clinic (OH). After an experience of about 15.000 vascular surgerie, in 2015 was appointed to Humanitas at the head of a relatively young team: the department of Vascular Surgery I. This department provides comprehensive treatments for all types of vascular disorders including the new technology of catheter-based intervention as well as traditional surgical treatment all geared toward maximizing safety and optimizing outcomes.

Prof. Civilini’s research has been focused on aortic surgery and minimally invasive vascular therapies. He co-authored practice guidelines for the treatment of patients with cardiovascular diseases and has played a role in industry-sponsored clinical trials assessing the performance of new expandable stents used to treat thoracic aorta disease. He has been invited to present his clinical experience at international and national medical conferences and symposia.

He has authored or co-authored several peer-reviewed articles and book chapters on his clinical experience and research. He serves as a reviewer for the Annals of Vascular Surgery and is member of the European Society of Vascular Surgery and the Società Italiana di Chirurgia Vascolare ed Endovascolare.

Previous experience:

1995-2014
Scientific Institute San Raffaele, Milan. Italy
Staff surgeon and Director of the Thoracic Aortic Surgery

2003-2014
“Vita – Salute” University, Milan. Italy
Fellow and Contract Professor of Surgery

2008 
Cleveland Clinic, Cleveland (OH)
Additional training in catheter-based interventions and endovascular surgery of thoraco-abdominal aneurysms.

Publications:

http://www.ncbi.nlm.nih.gov/pubmed/?term=Civilini%20E%5BAuthor%5D&cauthor=true&cauthor_uid=26344379

Prof. Carlo Castroro is the General Gastric and Esophagus Surgery Unit Director in Humanitas Research Hospital. He has graduated in the University of Padua and specialised in general medicine and thoracic surgery.

Medical areas of interest:

• gastric esophagus surgery
• day surgery
• general surgery

Previous experience:

Head of Simple Departmental Oncological Surgery Unit at the “Istituto Oncologico Veneto”, IOV - IRCCS, Padua.

Research areas of interest: 

• gastro-intestinal oncological surgery
• diseases of the esophagus with particular focus on oncologicy
• training, new technologies and distance learning
• day surgery and surgical services reorganization

Teaching experience: He is a professor in the Graduate School of General Surgery of the University of Padua and has also participated as a lecturer in numerous postgraduate training courses in the field of esophageal surgery, day surgery and minimally invasive surgery.

Publications: https://www.ncbi.nlm.nih.gov/pubmed/?term=castoro+carlo

Dr. Paolo Casale is the Urology Unit Director in Humanitas Research Hospital. 

Medical areas of interest: 
his main focus is surgical treatment of oncological and functional diseases of the kidney, bladder and prostate.

He has developed a particular interest in conservative oncological surgery of the kidneys, both traditional and minimally invasive (laparoscopic and robotic), and has dedicated himself to the study of prostate and bladder oncological pathologies, with particular attention to the different urinary derivations, such as orthotopic neobladders.

Research areas of interest:
Surgical techniques in the treatment of kidney, bladder and prostate cancer.

Previous experience:

• 1999 – 2014 University Hospital of Pisa – Pisa (PI), Italy
  Medical Director at the Urology Unit 2 (Reference Center for Kidney tumors) headed by Dr. Francesco Francesca. Here he served as the organization and surgical training manager in the operating room of Residents in Urology and Students of Degree in Medicine and Surgery.
• He has also held the following positions: 
•  
• May 2012 – May 2013: Head of the Section of Professional interdisciplinary relevance of Robot-assisted Laparoscopic Surgery 
•  
• Nov 2008 – April 2012: Head of the Robot assisted Laparoscopic Surgery
•  
• 1994 – 2004: Research Fellow in Laparoscopic Surgery and Robotics at the Glickman Urological Institute at The Cleveland Clinic Foundation on advanced laparoscopic procedures, Robotic Surgery and Minimally Invasive Surgery – Cleveland – USA. (Chief: IS Gill).
•  
• December 1995 – May 1996: Research Fellow at the Department of Urology, Henry Ford Hospital – Detroit – Michigan – USA. (Chief: JO Peabody).
•  
• 1994: Clinical Internship at the Department of Urology, Montefiore Medical Center – Albert Einstein ​​University – New York – USA. (Chief: A. Mellman).

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=casale p